Pathogenesis of Apical Periodontitis: a Literature Review

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Pathogenesis of Apical Periodontitis: a Literature Review

OBJECTIVES This review article discusses the host response in apical periodontitis with the main focus on cytokines, produced under this pathological condition and contributing to the degradation of periradicular tissues. The pace of research in this field has greatly accelerated in the last decade. Here we provide an analysis of studies published in this area during this period. MATERIAL AND...

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the importance of the role played by bacteria in the pathogenesis of pulpal and apical disease has been established. one of the characteristics of apical periodontitis is apical bone resorption, which is due to apical immune response to bacterial infection. recently, novel bacterial complex lipid called phosphorylated dihydroceramides has been discovered to be of inflammatory activators. the ba...

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Bacterial pathogenesis and mediators in apical periodontitis.

Apical periodontitis is a group of inflammatory diseases caused by microorganisms (mainly bacteria) infecting the necrotic root canal system. The pathogenesis of different types of apical periodontitis and even the same type in different individuals is unlikely to follow a stereotyped fashion with regard to the involved bacterial mediators. Disease pathogenesis is rather complex and involves a ...

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A Review of Novel Bacterial Complex Lipids: Implications for the Pathogenesis of Apical Periodontitis

The importance of the role played by bacteria in the pathogenesis of pulpal and apical disease has been established. One of the characteristics of apical periodontitis is apical bone resorption, which is due to apical immune response to bacterial infection. Recently, novel bacterial complex lipid called phosphorylated dihydroceramides has been discovered to be of inflammatory activators. The ba...

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The amounts of apical enlargement have been a controversial issue for a long time. The enlargement of the apical part of the canal may severely impact the endodontic prognosis. Enlargement of the apical portion to a larger size may negatively affect the ability to control the filling material during root canal obturation. In addition, an open-apex increases the risk for overfilling which has be...

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ژورنال

عنوان ژورنال: Journal of Oral and Maxillofacial Research

سال: 2011

ISSN: 2029-283X

DOI: 10.5037/jomr.2011.2401